Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins
Sign Up to like & getrecommendations! Published in 2022 at "Nature Biotechnology"
DOI: 10.1038/s41587-021-01112-1
Abstract: RNA-binding proteins (RBPs) play an essential role in regulating the function of RNAs in a cellular context, but our ability to control RBP activity in time and space is limited. Here, we describe the engineering… read more here.
Keywords: rna binding; control rna; function; binding proteins ... See more keywords
"Crowd-control" by RNA: A pervasive theme in biology.
Sign Up to like & getrecommendations! Published in 2023 at "RNA"
DOI: 10.1261/rna.079644.123
Abstract: As we continue to find new regulatory roles for RNAs, a theme is emerging in which regulation may not be mediated through the actions of a specific RNA, as one typically thinks of a regulator… read more here.
Keywords: control rna; theme; biology; rna pervasive ... See more keywords
Control of RNA degradation in cell fate decision
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1164546
Abstract: Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.… read more here.
Keywords: cell fate; cell; rna degradation; control rna ... See more keywords
Viscosity-Regulated Control of RNA Microstructure Fabrication
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DOI: 10.3390/polym13030454
Abstract: The development of RNA self-assemblies offers a powerful platform for a wide range of biomedical applications. The fabrication process has become more elaborate in order to achieve functional structures with maximized potential. As a facile… read more here.
Keywords: viscosity; control; regulated control; fabrication ... See more keywords