Dynamic Control of Signaling by Phosphorylation of PDZ Binding Motifs.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1166-1_11
Abstract: The dynamic regulation of protein-protein interactions (PPIs) involves phosphorylation of short liner motifs in disordered protein regions modulating binding affinities. The ribosomal-S6-kinase 1 is capable of binding to scaffold proteins containing PDZ domains through a… read more here.
Keywords: control signaling; dynamic control; pdz; pdz binding ... See more keywords
Control of Gαq signaling dynamics and GPCR cross-talk by GRKs
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq3363
Abstract: Numerous processes contribute to the regulation of G protein–coupled receptors (GPCRs), but relatively little is known about rapid mechanisms that control signaling on the seconds time scale or regulate cross-talk between receptors. Here, we reveal… read more here.
Keywords: cross talk; cross; signaling dynamics; control signaling ... See more keywords