The impact on estimations of genetic correlations by the use of super‐normal, unscreened, and family‐history screened controls in genome wide case–control studies
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22281
Abstract: Traditionally, in normal case–control studies of disorder A, the controls are defined as those not developing the disorder. However, in genome wide association (GWA) studies, controls are sometimes (a) unscreened or (b) screened for both… read more here.
Keywords: genome wide; control studies; genetic correlations; normal controls ... See more keywords
A Practical Overview of Case-Control Studies in Clinical Practice.
Sign Up to like & getrecommendations! Published in 2020 at "Chest"
DOI: 10.1016/j.chest.2020.03.009
Abstract: Case-control studies are one of the major observational study designs for performing clinical research. The advantages of these study designs over other study designs are that they are relatively quick to perform, economical, and easy… read more here.
Keywords: control studies; practical overview; case; study designs ... See more keywords
Case-Control Studies in Neurosurgery: the Issue of Effect Estimates.
Sign Up to like & getrecommendations! Published in 2022 at "World neurosurgery"
DOI: 10.1016/j.wneu.2022.03.097
Abstract: OBJECTIVE Clinical research questions are commonly answered using a case-control design. The decision to use this design is usually justified due to low cost, feasibility, and ease of execution. However, the case-control design presents challenges… read more here.
Keywords: case control; control studies; case; effect ... See more keywords
Association between IL-13 +1923C/T polymorphism and asthma risk: a meta-analysis based on 26 case-control studies
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience Reports"
DOI: 10.1042/bsr20160505
Abstract: Asthma is a serious and hereditary respiratory disorder affecting all age groups. Interleukin-13 (IL-13) is a central regulator of allergic inflammation. The purpose of the present study was to estimate the relationship between IL-13 +1923C/T… read more here.
Keywords: asthma; case control; control studies; 1923c polymorphism ... See more keywords
Hypothesis Tests for Neyman's Bias in Case–Control Studies
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DOI: 10.1080/02664763.2017.1401053
Abstract: ABSTRACT Survival bias is a long recognized problem in case–control studies, and many varieties of bias can come under this umbrella term. We focus on one of them, termed Neyman's bias or ‘prevalence–incidence bias’. It… read more here.
Keywords: control studies; hypothesis tests; case; neyman bias ... See more keywords
BSDE: barycenter single-cell differential expression for case–control studies
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac171
Abstract: Abstract Motivation Single-cell sequencing brings about a revolutionarily high resolution for finding differentially expressed genes (DEGs) by disentangling highly heterogeneous cell tissues. Yet, such analysis is so far mostly focused on comparing between different cell… read more here.
Keywords: cell; case control; single cell; control studies ... See more keywords
Sparse estimation for case-control studies with multiple disease subtypes.
Sign Up to like & getrecommendations! Published in 2020 at "Biostatistics"
DOI: 10.1093/biostatistics/kxz063
Abstract: The analysis of case-control studies with several disease subtypes is increasingly common, e.g. in cancer epidemiology. For matched designs, a natural strategy is based on a stratified conditional logistic regression model. Then, to account for… read more here.
Keywords: disease subtypes; case control; control studies;
How Often Do Orthopaedic Matched Case-Control Studies Use Matched Methods? A Review of Methodological Quality
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Orthopaedics and Related Research"
DOI: 10.1097/corr.0000000000000612
Abstract: Background Case-control studies are a common method of analyzing associations between clinical outcomes and potential risk factors. Matching cases to controls based on known confounding variables can decrease bias and allow investigators to assess the… read more here.
Keywords: number; case control; control studies; case ... See more keywords
Exposure to weak opioids and risk of gastrointestinal tract cancers: A series of nested case-control studies.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15759
Abstract: BACKGROUND There is evidence gastrointestinal (GI) motility may play a role in the development of GI cancers. Weak opioids (codeine and dihydrocodeine) decrease GI motility, but their effect on GI cancer risk has not been… read more here.
Keywords: weak opioids; control studies; series nested; nested case ... See more keywords
Marginal screening of 2 × 2 tables in large-scale case-control studies.
Sign Up to like & getrecommendations! Published in 2019 at "Biometrics"
DOI: 10.1111/biom.12957
Abstract: Assessing the statistical significance of risk factors when screening large numbers of 2 × 2 tables that cross-classify disease status with each type of exposure poses a challenging multiple testing problem. The problem is especially… read more here.
Keywords: large scale; control studies; marginal screening; case ... See more keywords
Gut microbial dysbiosis in rheumatoid arthritis: a systematic review protocol of case-control studies
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-052021
Abstract: Introduction Rheumatoid arthritis (RA) has a huge societal impact due to the high prevalence, irreversible joint damage and systemic complications. Gut microbiota plays an important role in the pathogenesis and progression of RA by regulating… read more here.
Keywords: microbial dysbiosis; control studies; dysbiosis; rheumatoid arthritis ... See more keywords