Mechano-Nanoswitches for Ultrasound-Controlled Drug Activation.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202104696
Abstract: Current pharmacotherapy is challenged by side effects and drug resistance issues due to the lack of drug selectivity. Mechanochemistry-based strategies provide new avenues to overcome the related problems by improving drug selectivity. It is recently… read more here.
Keywords: controlled drug; activation; drug; drug activation ... See more keywords
Electrospinning of stimuli‐responsive polymers for controlled drug delivery: pH‐ and temperature‐driven release
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28043
Abstract: Stimuli‐responsive polymers have attracted academic interest over the last 60 years due to their potential use in developing systems with a range of functionalities that can be activated by external artificial triggers. The diversity of… read more here.
Keywords: responsive polymers; stimuli responsive; controlled drug; drug delivery ... See more keywords
Ion Exchange Controlled Drug Release from Polymerized Ionic Liquids.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202000152
Abstract: In this work ion functionalized hydrogels as potent drug delivery systems are presented. The ion functionalization of the hydrogel enables the retention of ionic drug molecules and thus a reduction of burst release effects. Timolol… read more here.
Keywords: ion exchange; drug; drug release; controlled drug ... See more keywords
3D Composite Assemblies of Microparticles and Nanofibers for Tailored Wettability and Controlled Drug Delivery
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular Materials and Engineering"
DOI: 10.1002/mame.201600458
Abstract: The control of the drug release kinetics is of prime importance for the design of bioactive nanofibrous membrane. Whereas simple drug-loaded electrospun poly(lactic acid) (PLA) nanofibrous membranes have a hydrophobic behavior with a water contact… read more here.
Keywords: nanofibrous membranes; drug delivery; delivery; drug ... See more keywords
Targeted and Controlled Drug Delivery to a Rat Model of Heart Failure Through a Magnetic Nanocomposite
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-019-02394-y
Abstract: As a novel cardiac myosin activator, Omecamtive Mecarbil (OM) has shown promising results in the management of systolic heart failure in clinical examinations. However, the need for repeated administration along with dose-dependent side effects made… read more here.
Keywords: heart; delivery; heart failure; targeted controlled ... See more keywords
Bioresorbable Scaffold-Based Controlled Drug Delivery for Restenosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-018-9841-x
Abstract: Bioresorbable scaffolds have emerged as a potential alternative to non-erodible metal implants to alleviate the long-term risk of permanent device vascular implant-related adverse events. Bioresorbable scaffolds provide a temporary mechanical support function until the vessel… read more here.
Keywords: scaffold based; drug; based controlled; bioresorbable scaffold ... See more keywords
Polyurethane-based hydrogels for controlled drug delivery applications
Sign Up to like & getrecommendations! Published in 2020 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2019.109444
Abstract: Abstract The aim of this paper was to prepare polyurethane-based hydrogels for the controlled release of 5-fluoro uracil. The polyurethane containing azomethine linkage in the main chain was prepared using different diisocyanates such as HDI,… read more here.
Keywords: based hydrogels; drug delivery; polyurethane based; controlled drug ... See more keywords
pH-Controlled drug delivery with hybrid aerogel of chitosan, carboxymethyl cellulose and graphene oxide as the carrier.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.064
Abstract: Hybrid aerogels of chitosan (CS), carboxymethyl cellulose (CMC) and graphene oxide (GO) are successfully prepared by using calcium ion (Ca2+) as the crosslinker. The resultant hybrid aerogels, CS/CMC/Ca2+/GO, are characterized by field emission scanning electron… read more here.
Keywords: drug delivery; chitosan carboxymethyl; carboxymethyl cellulose; drug ... See more keywords
Design of a pH-responsive oral gel formulation based on the matrix systems of gelatin/hydroxypropyl methylcellulose phthalate for controlled drug release.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120047
Abstract: Extensive efforts have been directed toward developing novel easily digested formulations with desirable controlled-release properties. The present study sought to develop pH-responsive oral gel formulations using combinations of gelatin and enteric polymers for controlled drug… read more here.
Keywords: responsive oral; drug release; oral gel; controlled drug ... See more keywords
Nanocomposite clay-polymer microbeads for oral controlled drug delivery: Development and, in vitro and in vivo evaluations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.03.001
Abstract: The aim of the present study was to design microbeads by using nanocomposite clays (Optigel (OPT) and Laponite (LAP)) and polymers (sodium alginate (SA) and chitosan (CS)) for controlled release of diclofenac sodium (DS). Microbeads… read more here.
Keywords: drug; clay polymer; vitro; drug delivery ... See more keywords
Production and characterization of a new pH-responsive shellac system for controlled drug release
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128382
Abstract: Abstract A new carrier platform was designed based on shellac wax-albumin for controlled drug delivery. For this purpose, human serum albumin (HSA) was immobilized on various amounts of shellac wax (W). Then, glutathione (G) and… read more here.
Keywords: microscopy; shellac; drug; spectroscopy ... See more keywords