Controlling the regioselectivity of the bromolactonization reaction in HFIP
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DOI: 10.1039/d4sc01503g
Abstract: The halolactonization reaction provides rapid access to densely functionalized lactones from unsaturated carboxylic acids. The endo/exo regioselectivity of this cyclization reaction is primarily determined by the electronic stabilization of alkene substituents, thus making it inherently… read more here.
Keywords: reaction; regioselectivity bromolactonization; regioselectivity; controlling regioselectivity ... See more keywords