Separase prevents genomic instability by controlling replication fork speed
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DOI: 10.1093/nar/gkx1172
Abstract: Abstract Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development. Sister chromatid separation is triggered by Separase, an evolutionary conserved protease… read more here.
Keywords: controlling replication; genomic instability; separase; fork ... See more keywords