Controlling Stereopreferences of Carbonyl Reductases for Enantioselective Synthesis of Atorvastatin Precursor
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DOI: 10.1021/acscatal.0c05607
Abstract: Carbonyl reductase (CR)-catalyzed asymmetric reduction offers an approach for producing t-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate ((3R,5R)-1b), which serves as a key building block in atorvastatin... read more here.
Keywords: carbonyl reductases; controlling stereopreferences; stereopreferences carbonyl; enantioselective synthesis ... See more keywords