Regulating the Master Regulator: Controlling Ubiquitination by Thinking Outside the Active Site.
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DOI: 10.1021/acs.jmedchem.6b01346
Abstract: The labeling of proteins with ubiquitin/ubiquitin-like (Ubl) proteins is crucial for several physiological processes and in the onset of various diseases. Recently, targeting ubiquitin protein labeling has shifted toward the use of allosteric mechanisms over… read more here.
Keywords: regulating master; active site; site; master regulator ... See more keywords