Liraglutide provides neuroprotection by regulating autophagy through the AMPK-FOXO3 signaling pathway in a spinal contusion injury rat model
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134747
Abstract: Spinal cord injury (SCI) induced by trauma is a devasting neurological consequences. Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, has be shown to have neuroprotective effects in several neurodegenerative diseases. However, the potential benefits of liraglutide… read more here.
Keywords: ampk foxo3; spinal contusion; contusion; foxo3 signaling ... See more keywords
Diaphragm muscle function following midcervical contusion injury in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00481.2018
Abstract: Midcervical spinal cord contusion injury results in tissue damage, disruption of spinal pathways, and motor neuron loss. Unilateral C4 contusion results in loss of 40%-50% of phrenic motor neurons ipsilateral to the injury (~25% of… read more here.
Keywords: unilateral contusion; muscle; contusion; motor ... See more keywords
An experimental model of contusion injury in humans
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277765
Abstract: Introduction Contusion injuries are common in sport, but our knowledge of the responses to injury primarily come from animal studies and research using eccentric exercise. Therefore, the aim of this study was to develop a… read more here.
Keywords: contusion injury; impact; force; model contusion ... See more keywords