Development and Validation of a Treatment Benefit Index to Identify Hospitalized Patients With COVID-19 Who May Benefit From Convalescent Plasma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.47375
Abstract: Key Points Question What patient characteristics are associated with benefit from treatment with COVID-19 convalescent plasma (CCP)? Findings This prognostic study of 2287 patients hospitalized with COVID-19 identified a combination of baseline characteristics that predict… read more here.
Keywords: benefit; treatment; convalescent plasma; treatment benefit ... See more keywords
Heterogeneity in COVID‐19 Convalescent Plasma Clinical Trials
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2281
Abstract: Due to the outbreak of the coronavirus disease 2019 (COVID19) pandemic, clinical trial (CT) research for efficacy and safety evaluation of convalescent plasma (CP) accelerated globally. In trial planning and approval, clinical researcher and regulatory… read more here.
Keywords: convalescent; covid convalescent; convalescent plasma; heterogeneity covid ... See more keywords
LACK OF EFFICACY OF CONVALESCENT PLASMA IN COVID-19 PATIENTS WITH CONCOMITANT HEMATOLOGICAL MALIGNANCIES AN ITALIAN RETROSPECTIVE STUDY.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3060
Abstract: A multicenter retrospective study was designed to assess clinical outcome of COVID-19 in patients with hematological malignancies (HM) following treatment with anti-SARS-CoV-2 convalescent plasma (CP) or standard of care therapy. To this aim, a propensity… read more here.
Keywords: covid patients; retrospective study; covid; hematological malignancies ... See more keywords
A matched cohort study of convalescent plasma therapy for COVID‐19
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21888
Abstract: COVID‐19, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is a public health crisis. Prior studies demonstrated successful use of convalescent plasma therapy for treatment of other viral illnesses. Our primary objective was to… read more here.
Keywords: plasma therapy; convalescent plasma; plasma; covid ... See more keywords
Analysis of responses of the health care workers recovered from COVID-19 on convalescent plasma donation by apheresis: A single-center survey study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical apheresis"
DOI: 10.1002/jca.21970
Abstract: BACKGROUND The COVID-19 convalescent plasma (CCP) has been tried as a therapy in moderate COVID-19 pneumonia. Donation of CCP requires motivation from recovered patients. This study evaluated the response of such recovered health care workers… read more here.
Keywords: study; health care; donation; covid convalescent ... See more keywords
COVID‐19 therapy with mesenchymal stromal cells (MSC) and convalescent plasma must consider exosome involvement: Do the exosomes in convalescent plasma antagonize the weak immune antibodies?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12004
Abstract: Abstract Exosome extracellular vesicles as biologic therapy for COVID‐19 are discussed for two areas. The first involves the growing use of mesenchymal stromal cells (MSCs) for the profound clinical cytokine storm and severe pneumonia in… read more here.
Keywords: mesenchymal stromal; plasma; immune antibodies; stromal cells ... See more keywords
Convalescent plasma for the treatment of patients with severe coronavirus disease 2019: A preliminary report
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26537
Abstract: The role of convalescent plasma therapy for patients with coronavirus disease 2019 (COVID‐19) is unclear. read more here.
Keywords: disease 2019; treatment patients; plasma treatment; convalescent plasma ... See more keywords
A review of mass spectrometry‐based analyses to understand COVID‐19 convalescent plasma mechanisms of action
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DOI: 10.1002/pmic.202200118
Abstract: The spread of coronavirus disease 2019 (COVID‐19) viral pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has become a worldwide pandemic claiming several thousands of lives worldwide. During this pandemic, several studies reported… read more here.
Keywords: mass spectrometry; covid convalescent; plasma; convalescent plasma ... See more keywords
Severe COVID-19 in Patients with B Cell Alymphocytosis and Response to Convalescent Plasma Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-020-00904-5
Abstract: To the Editor, The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease 2019 (COVID-19), has resulted in a global pandemic. In most cases, COVID-19 is a self-limited infection… read more here.
Keywords: covid patients; cell alymphocytosis; covid; patients cell ... See more keywords
Neutralizing Autoantibodies to Type I Interferons in COVID-19 Convalescent Donor Plasma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-021-01060-0
Abstract: Convalescent plasma has been a mainstay therapeutic in passive immunization for decades. In the setting of the novel coronavirus (SARS-CoV-2), it has become widely used for prophylaxis and early intervention in COVID-19 [1, 2]. Recently,… read more here.
Keywords: type interferons; plasma; donor; covid ... See more keywords
Convalescent plasma as a treatment modality for Coronavirus Disease 2019 in Indonesia: A case reports
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.102444
Abstract: Introduction and Importance: Coronavirus Disease 2019 (COVID-19) has become a pandemic since the beginning of 2020. COVID-19 is also spreading very rapidly in Indonesia and so far, no definitive therapy has been found. Case presentation… read more here.
Keywords: convalescent plasma; disease 2019; coronavirus disease; convalescent ... See more keywords