Articles with "convenient free" as a keyword



A Convenient, Pd-Free Approach to the Synthesis of Risdiplam

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Published in 2025 at "Molecules"

DOI: 10.3390/molecules30163375

Abstract: Several approaches to the synthesis of risdiplam, a pharmacologically relevant pyridopyrimidinone derivative, have been recently reported. However, most of these routes rely exclusively on palladium-catalyzed, cross-coupling reactions and involve low-yielding intermediates, which limit their scalability… read more here.

Keywords: risdiplam; synthesis; free approach; synthesis risdiplam ... See more keywords