Intratumoral Comparison of Nanoparticle Entrapped Docetaxel (CPC634) with Conventional Docetaxel in Patients with Solid Tumors
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DOI: 10.1158/1078-0432.ccr-20-0008
Abstract: Purpose: CPC634 is a novel nanoparticle entrapping docetaxel, developed to enhance the intratumoral chemotherapy exposure. This randomized cross-over study compared the intratumoral and plasma pharmacokinetics of CPC634 with conventional docetaxel. Patients and Methods: Adult patients… read more here.
Keywords: docetaxel patients; conventional docetaxel; cpc634 conventional; nanoparticle ... See more keywords
Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension (NDLS) versus Conventional Docetaxel as Neoadjuvant and Adjuvant Therapy for Primary Operable Breast Cancer
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DOI: 10.2147/ott.s400824
Abstract: Objective Nanosomal docetaxel lipid suspension (NDLS) is a novel formulation developed to overcome toxicity issues caused by excipients (polysorbate 80 and ethanol) present in commercially available docetaxel formulation. We conducted a prospective, observational study to… read more here.
Keywords: breast cancer; conventional docetaxel; docetaxel; ndls ... See more keywords