New insights into non-conventional epitopes as T cell targets: The missing link for breaking immune tolerance in autoimmune disease?
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DOI: 10.1016/j.jaut.2017.08.001
Abstract: The mechanism by which immune tolerance is breached in autoimmune disease is poorly understood. One possibility is that post-translational modification of self-antigens leads to peripheral recognition of neo-epitopes against which central and peripheral tolerance is… read more here.
Keywords: non conventional; immune tolerance; cell targets; conventional epitopes ... See more keywords