Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
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DOI: 10.1016/j.immuni.2021.02.013
Abstract: Human IGHV1-69-encoded broadly neutralizing antibodies (bnAbs) that target the hepatitis C virus (HCV) envelope glycoprotein (Env) E2 are important for protection against HCV infection. An IGHV1-69 ortholog gene, VH1.36, is preferentially used for bnAbs isolated… read more here.
Keywords: germline encoded; hcv; convergence germline; rhesus macaques ... See more keywords