Combined Theoretical and Experimental Studies Unravel Multiple Pathways to Convergent Asymmetric Hydrogenation of Enamides
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DOI: 10.1021/jacs.1c09573
Abstract: We present a highly efficient convergent asymmetric hydrogenation of E/Z mixtures of enamides catalyzed by N,P–iridium complexes supported by mechanistic studies. It was found that reduction of the olefinic isomers (E and Z geometries) produces… read more here.
Keywords: hydrogenation; convergent asymmetric; combined theoretical; theoretical experimental ... See more keywords