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Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.

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0 Published in 2019 at "Cell systems"

DOI: 10.1016/j.cels.2019.01.004

Abstract: The genetic makeup of cancer cells directs oncogenesis and influences the tumor microenvironment. In this study, we massively profiled genes that functionally drive tumorigenesis using genome-scale in vivo CRISPR screens in hosts with different levels of… read more here.

Keywords: convergent identification; interrogation; cancer; tumor microenvironment ... See more keywords