Articles with "converging mechanism" as a keyword



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Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases

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Published in 2018 at "Current Opinion in Neurobiology"

DOI: 10.1016/j.conb.2017.09.005

Abstract: Endo-lysosomal pathways are essential in maintaining protein homeostasis in the cell. Numerous genes in the endo-lysosomal pathways have been found to associate with neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and frontotemporal dementia… read more here.

Keywords: endo lysosomal; dysfunction; neurodegenerative diseases; lysosomal dysfunction ... See more keywords