Stereoretentive Conversion to C-Glycosides from S-Glycosides via Ligand-Coupling on Sulfur(IV).
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DOI: 10.1021/acs.orglett.4c04338
Abstract: A novel strategy is reported for the stereoselective synthesis of C(sp2)-C(sp3) C-glycosides, which converts heteroaryl S-glycosides into heteroaryl C-glycosides with retention of configuration through a sequential process involving oxidation and Grignard reagent attack. The new… read more here.
Keywords: glycosides via; heteroaryl glycosides; ligand coupling; conversion glycosides ... See more keywords