Incorporating cortisol into the NAPLS2 individualized risk calculator for prediction of psychosis
Sign Up to like & getrecommendations! Published in 2021 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2020.09.022
Abstract: BACKGROUND Risk calculators are useful tools that can help clinicians and researchers better understand an individual's risk of conversion to psychosis. The North American Prodrome Longitudinal Study (NAPLS2) Individualized Risk Calculator has good predictive accuracy… read more here.
Keywords: cortisol; risk; conversion psychosis; psychosis ... See more keywords
Longitudinal Analyses of Blood Transcriptome During Conversion to Psychosis
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sby009
Abstract: The biological processes associated with the onset of schizophrenia remain largely unknown. Current hypotheses favor gene × environment interactions as supported by our recent report about DNA methylation changes during the onset of psychosis. Here,… read more here.
Keywords: longitudinal analyses; analyses blood; blood transcriptome; conversion ... See more keywords
Altered Brain Activation During Memory Retrieval Precedes and Predicts Conversion to Psychosis in Individuals at Clinical High Risk.
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sby122
Abstract: Memory deficits are a hallmark of psychotic disorders such as schizophrenia. However, whether the neural dysfunction underlying these deficits is present before the onset of illness and potentially predicts conversion to psychosis is unclear. In… read more here.
Keywords: memory retrieval; high risk; conversion psychosis; memory ... See more keywords
Prediction of conversion to psychosis in individuals with an at-risk mental state: a brief update on recent developments
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Psychiatry"
DOI: 10.1097/yco.0000000000000320
Abstract: Purpose of review So far, only little more than one-third of individuals classified as being at-risk for psychosis have been shown to actually convert to frank psychosis during follow-up. There have therefore been enormous efforts… read more here.
Keywords: risk; prediction conversion; conversion psychosis; prediction ... See more keywords
Antipsychotics are related to psychometric conversion to psychosis in ultra-high-risk youth.
Sign Up to like & getrecommendations! Published in 2021 at "Early intervention in psychiatry"
DOI: 10.1111/eip.13158
Abstract: BACKGROUND The prescription of antipsychotics outside overt psychotic conditions remains controversial, especially in youth where it is relatively widespread. Furthermore, some studies seem to indicate that antipsychotic exposure in individuals at ultra-high-risk (UHR) for psychosis… read more here.
Keywords: risk; conversion; conversion psychosis; prescription antipsychotics ... See more keywords