Conversion surgery after preoperative therapy for advanced hepatocellular carcinoma in the era of molecular targeted therapy and immune checkpoint inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hepato-biliary-pancreatic sciences"
DOI: 10.1002/jhbp.1135
Abstract: Optimal strategies for advanced HCC tumors, such as those with vascular tumor thrombus and those with extrahepatic metastases, are unclear. Upfront surgical resection of such tumors has been challenged at some institutions because of lack… read more here.
Keywords: conversion surgery; therapy; unresectable hcc; conversion ... See more keywords
Role of Conversion Surgery for Unresectable Pancreatic Cancer After Long-Term Chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Surgery"
DOI: 10.1007/s00268-020-05503-4
Abstract: Background Unresectable pancreatic cancer (UR-PC) has a poor prognosis. Although conversion surgery has been considered a promising strategy for improving prognosis in UR-PC, the clinical benefit offered to patients with UR-PC remains controversial. This study… read more here.
Keywords: long term; surgery; unresectable pancreatic; conversion surgery ... See more keywords
Outcomes of conversion surgery following chemotherapy for initially unresectable metastatic pancreatic ductal adenocarcinoma: a retrospective cohort study in Taiwan
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-025-06353-0
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a high mortality rate. For patients with metastatic PDAC (mPDAC) initially deemed unresectable, systemic chemotherapy followed by conversion surgery may offer an improvement in survival. This… read more here.
Keywords: pancreatic ductal; conversion; chemotherapy; study ... See more keywords
Successful intrahepatic cholangiocarcinoma conversion surgery after administration of fibroblast growth factor receptor inhibitor
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-024-02014-w
Abstract: We describe a case of a 47-year-old male patient with initially unresectable intrahepatic cholangiocarcinoma of the right liver lobe with tumor thrombi extending from the right bile duct to the common and left bile ducts.… read more here.
Keywords: fibroblast growth; intrahepatic cholangiocarcinoma; factor receptor; growth factor ... See more keywords
P2.01-08 Conversion Surgery for Locally Advanced Lung Adenocarcinoma Harboring Driver Gene Mutation After TKI Followed by Cytotoxic Agent
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.08.1062
Abstract: was conducted to compare gender-based post diagnosis survival and disease progression. Statistical significance was 95% confidence level (p < 0.05). Result: Among 7738 lung cancer patients, 95.6% (3743/ 7738) were NSCLC: 52% male and 48%… read more here.
Keywords: advanced lung; histology; surgery locally; locally advanced ... See more keywords
Abstract 3750: Conversion surgery in unresectable advanced gastric cancer and cancer dormancy as a prognostic marker
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-3750
Abstract: Background: While additional gastrectomy has not shown superiority compared to conventional systemic therapy in unresectable gastric cancer in REGATTA trial, there have been several subsequent attempts to find a role for conversion surgery with a… read more here.
Keywords: conversion surgery; gastric cancer; cancer dormancy; cancer ... See more keywords
Long-term Outcomes for Late-Phase Kienböck's Tenoarthroplasty.
Sign Up to like & getrecommendations! Published in 2022 at "Hand"
DOI: 10.1177/15589447221136622
Abstract: BACKGROUND In late Kienbӧck's, the lunate is fully fragmented and nonreconstructible. Replacing the lunate with a pyrocarbon prosthesis preserves load distribution and avoids carpectomy or fusion, but leaves the wrist intrinsically unstable, requiring additional soft-tissue… read more here.
Keywords: long term; conversion surgery; outcomes late; surgery ... See more keywords
Impact of CD44/326 peritoneal cells as response indicators in advanced gastric cancer patients receiving repeated intraperitoneal perfusion normothermic chemotherapy
Sign Up to like & getrecommendations! Published in 2025 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359251337480
Abstract: Background: In gastric cancer (GC), the dissemination of neoplastic cells (NCs) in the peritoneal cavity is related to disease progression and poor prognosis. Elimination of NC through chemotherapy is needed to achieve better outcomes before… read more here.
Keywords: cd44 cd326; impact cd44; gastric cancer; chemotherapy ... See more keywords
Higher Age is Associated with Lower Likelihood of Conversion to Surgery after Primary Nonoperative Treatment for Osteochondral Lesions of the Talus.
Sign Up to like & getrecommendations! Published in 2024 at "Cartilage"
DOI: 10.1177/19476035241227357
Abstract: INTRODUCTION The first line of treatment for osteochondral lesions of the talus (OLT) is nonoperative. To date, there is limited evidence on risk factors that may influence conversion to surgery after primary nonoperative treatment for… read more here.
Keywords: age; treatment; conversion; risk ... See more keywords
Optimal preoperative treatment strategy for conversion surgery in unresectable locally advanced pancreatic cancer: A project study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.4_suppl.718
Abstract: 718 Background: Conversion surgery (CS) for unresectable locally advanced pancreatic cancer (UR-LAPC) has been widely accepted when feasible. However, optimal preoperative treatment strategies remain unclear. To determine the most effective preoperative approach for UR-LAPC in… read more here.
Keywords: treatment; preoperative treatment; surgery unresectable; optimal preoperative ... See more keywords
Surgical Outcome and Long-Term Survival of Conversion Surgery for Advanced Gastric Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-08559-7
Abstract: Background The present study aims to report the surgical outcome and long-term survival of conversion surgery and clarify its role in advanced gastric cancer. Patients and Methods A total of 95 primary advanced gastric adenocarcinoma… read more here.
Keywords: survival conversion; advanced gastric; gastric cancer; conversion ... See more keywords