Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.
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DOI: 10.1016/j.exphem.2019.03.003
Abstract: Reduced expression of the transcription factor PU.1 is frequently associated with development of acute myeloid leukemia (AML), whereas elevated levels of CITED2 (CBP/p300-interacting-transactivator-with-an-ED-rich-tail 2) enhance maintenance of both normal and leukemic hematopoietic stem and progenitor… read more here.
Keywords: cooperate maintaining; transcriptional regulators; cited2 cooperate; hematopoietic stem ... See more keywords