Cooperative pro-tumorigenic adaptation to oncogenic RAS through epithelial-to-mesenchymal plasticity
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DOI: 10.1126/sciadv.adi1736
Abstract: In breast cancers, aberrant activation of the RAS/MAPK pathway is strongly associated with mesenchymal features and stemness traits, suggesting an interplay between this mitogenic signaling pathway and epithelial-to-mesenchymal plasticity (EMP). By using inducible models of… read more here.
Keywords: tumorigenic adaptation; mesenchymal plasticity; epithelial mesenchymal; cooperative pro ... See more keywords