Succinate and inosine coordinate innate immune response to bacterial infection
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DOI: 10.1371/journal.ppat.1010796
Abstract: Macrophages restrict bacterial infection partly by stimulating phagocytosis and partly by stimulating release of cytokines and complement components. Here, we treat macrophages with LPS and a bacterial pathogen, and demonstrate that expression of cytokine IL-1β… read more here.
Keywords: inosine; coordinate innate; bacterial infection; inosine coordinate ... See more keywords