GOLD assessment of COPD severity in the Clinical Practice Research Datalink (CPRD)
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4448
Abstract: To evaluate availability of spirometry and symptom data in the Clinical Practice Research Datalink (United Kingdom) to assess COPD severity using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2016 definition and comparing it… read more here.
Keywords: research datalink; practice research; copd severity; clinical practice ... See more keywords
Authors reply: Dual versus single longâacting bronchodilator use could raise acute coronary syndrome risk by over 50%
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13439
Abstract: As noted in our paper, we cannot rule out the possibility of some residual confounding by indication [1]. However, the concern of Almagro et al. [2] that confounding by indication could have been a substantive… read more here.
Keywords: severity; acting bronchodilator; long acting; copd severity ... See more keywords
Serum levels of hyaluronic acid are associated with COPD severity and predict survival
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DOI: 10.1183/13993003.01183-2018
Abstract: Hyaluronic acid (HA) and its degradation products play an important role in lung pathophysiology and airway remodelling in chronic obstructive pulmonary disease (COPD). We investigated if HA and its degrading enzyme hyaluronidase (HYAL)-1 are associated… read more here.
Keywords: copd severity; hyaluronic acid; associated copd; serum ... See more keywords
Testosterone levels and their association with COPD severity: A cross sectional study.
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DOI: 10.1183/13993003.congress-2018.pa3624
Abstract: Introduction: The prevalence of hypogonadism in COPD patients is higher than in the general population and can range from 22 to 69%. However, the association between testosterone levels and COPD severity is controversial. The aim… read more here.
Keywords: association; copd severity; testosterone levels; testosterone ... See more keywords
Frailty and social, clinical, and CT imaging factors in COPD: a multicenter study
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DOI: 10.1183/23120541.01213-2025
Abstract: Frailty often coexists in patients with chronic obstructive pulmonary disease (COPD) regardless of disease severity and may serve as a treatable trait. We hypothesized that factors associated with frailty may differ by COPD severity. This… read more here.
Keywords: disease; copd severity; frailty; study ... See more keywords
Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity
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DOI: 10.1186/s12931-017-0522-0
Abstract: BackgroundIt is known that tissue macrophages derive not only from blood monocytes but also from yolk sac or fetal liver, and the tissue of residence guides their function. When isolated, they lose tissue specific signatures,… read more here.
Keywords: smoking copd; polarization; copd severity; alveolar macrophages ... See more keywords
Effect of COPD severity and comorbidities on the result of the PHQ-9 tool for the diagnosis of depression: results from the COSYCONET cohort study
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DOI: 10.1186/s12931-019-0997-y
Abstract: The diagnosis of depression, a frequent comorbidity of chronic obstructive pulmonary disease (COPD), is often supported by questionnaires, such as the Patient Health Questionnaire 9 (PHQ-9). It is unknown to which extent its single questions… read more here.
Keywords: depression; copd severity; diagnosis; copd ... See more keywords