Articles with "copies negatively" as a keyword



Additional copies of 1q negatively impact the outcome of multiple myeloma patients and induce transcriptomic deregulation in malignant plasma cells

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Published in 2024 at "Blood Cancer Journal"

DOI: 10.1038/s41408-024-01075-x

Abstract: Additional copies of chromosome 1 long arm (1q) are frequently found in multiple myeloma (MM) and predict high-risk disease. Available data suggest a different outcome and biology of patients with amplification (Amp1q, ≥4 copies of… read more here.

Keywords: multiple myeloma; deregulation; gain1q; copies negatively ... See more keywords