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   Articles with "copii" as a keyword



Hanging the coat on a collar: Same function but different localization and mechanism for COPII

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recommendations! Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202200064

Abstract: An entirely different mechanism and localization were recently proposed for the COPII coat complex, challenging its well‐accepted function to select and concentrate cargo into small COPII‐coated spherical transport vesicles. Instead, the COPII complex is suggested… read more here.

Keywords: function; localization; coat; transport ... See more keywords
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A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana.

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recommendations! Published in 2021 at "Nature plants"

DOI: 10.1038/s41477-021-00997-9

Abstract: Plants live as sessile organisms with large-scale gene duplication events and subsequent paralogue divergence during evolution. Notably, plant paralogues are expressed tissue-specifically and fine-tuned by phytohormones during various developmental processes. The coat protein complex II… read more here.

Keywords: protein complex; arabidopsis; coat protein; copii ... See more keywords

Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep43207

Abstract: The Transport protein particle (TRAPP) complex is a tethering factor for COPII vesicle. Of three forms of TRAPP (TRAPPI, II and III) complexes identified so far, TRAPPIII has been largely considered to play a role… read more here.

Keywords: trappiii; mammalian trappiii; trappiii complex; copii ... See more keywords

Myotubularin 2 interacts with SEC23A and negatively regulates autophagy at ER exit sites in Arabidopsis

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recommendations! Published in 2024 at "Autophagy"

DOI: 10.1080/15548627.2024.2394302

Abstract: ABSTRACT Starvation- or stress-induced phosphatidylinositol 3-phosphate (PtdIns3P/PI3P) production at the endoplasmic reticulum (ER) subdomains organizes phagophore assembly and autophagosome formation. Coat protein complex II (COPII) vesicles budding from ER exit site (ERES) also contribute to… read more here.

Keywords: regulates autophagy; ptdins3p; mtm2; negatively regulates ... See more keywords

The disruption of COPII vesicles activates HSF-1 through SEC-23.

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recommendations! Published in 2025 at "Journal of molecular cell biology"

DOI: 10.1093/jmcb/mjaf017

Abstract: Abstract HSF-1 is a highly conserved transcription factor that plays a central role in protecting organisms from diverse cellular stresses. However, the mechanisms by which HSF-1 senses and responds to different types of stress remain… read more here.

Keywords: copii vesicle; copii vesicles; disruption; copii ... See more keywords

Stage-Specific COPII-Mediated Cargo Selectivity in African Trypanosomes

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recommendations! Published in 2022 at "mSphere"

DOI: 10.1128/msphere.00188-22

Abstract: African trypanosomes synthesize dense surface coats composed of stage-specific glycosylphosphatidylinositol lipid anchored proteins. We previously defined specific machinery in bloodstream stage parasites that mediate the exit of these proteins from the endoplasmic reticulum. ABSTRACT A… read more here.

Keywords: stage specific; tbsec23 tbsec24; african trypanosomes; stage ... See more keywords

SEC24C deficiency causes trafficking and glycosylation abnormalities in an epileptic encephalopathy with cataracts and dyserythropoeisis

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recommendations! Published in 2025 at "JCI Insight"

DOI: 10.1172/jci.insight.173484

Abstract: As a major component of intracellular trafficking, the coat protein complex II (COPII) is indispensable for cellular function during embryonic development and throughout life. The 4 SEC24 proteins (A–D) are essential COPII components involved in… read more here.

Keywords: sec24c; sec24c deficiency; copii; deficiency causes ... See more keywords

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

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recommendations! Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-111628

Abstract: T cells play critical roles in both protective and pathogenic adaptive immune responses. The release of cytokines by T cells is critical for their development, differentiation, and effector functions. However, significant gaps remain in our… read more here.

Keywords: copii; deficient cells; cell; sec23b deficient ... See more keywords

Essential Role of COPII Proteins in Maintaining the Contractile Ring Anchoring to the Plasma Membrane during Cytokinesis in Drosophila Male Meiosis

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms25084526

Abstract: Coatomer Protein Complex-II (COPII) mediates anterograde vesicle transport from the endoplasmic reticulum (ER) to the Golgi apparatus. Here, we report that the COPII coatomer complex is constructed dependent on a small GTPase, Sar1, in spermatocytes… read more here.

Keywords: male meiosis; copii; drosophila male; plasma membrane ... See more keywords