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   Articles with "copine" as a keyword



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Copine A regulates the size and exocytosis of contractile vacuoles and postlysosomes in Dictyostelium

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12874

Abstract: Copines are a family of cytosolic proteins that associate with membranes in a calcium‐dependent manner and are found in many eukaryotic organisms. Dictyostelium discoideum has six copine genes (cpnA‐cpnF), and cells lacking cpnA(cpnA−) have defects… read more here.

Keywords: cpna cells; cpna; copine; contractile vacuoles ... See more keywords
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Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib

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recommendations! Published in 2018 at "Cancer Management and Research"

DOI: 10.2147/cmar.s167781

Abstract: Background The application of the oral targeted therapeutic agent sorafenib provides new hope for patients suffering from advanced stages of hepatocellular carcinoma (HCC), but the prognosis of such patients remains poor due to the rapid… read more here.

Keywords: expression copine; copine iii; copine; sorafenib ... See more keywords
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Prognostic Value of Copine 1 in Patients With Renal Cell Carcinoma

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recommendations! Published in 2021 at "AntiCancer Research"

DOI: 10.21873/anticanres.15493

Abstract: Background/Aim: Renal cell carcinoma (RCC) is among the most common renal malignancies and requires reliable biomarkers for optimum diagnosis and prognosis. Copines are a family of calcium-dependent phospholipid-binding proteins that were reported to be associated… read more here.

Keywords: renal cell; cell carcinoma; copine; prognostic value ... See more keywords
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BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats

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recommendations! Published in 2018 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2018.00731

Abstract: Chronic stress is a contributing risk factor in the pathogenesis of depression. Although the mechanisms are multifaceted, the relationship can be ascribed partly to stress-related alterations in immune activation and brain plasticity. Considering the increasing… read more here.

Keywords: depression; copine; test; synaptic plasticity ... See more keywords
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Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC

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recommendations! Published in 2019 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2019.01544

Abstract: Quercetin is a polyphenol with multiple biological activities, and results of our preliminary study showed that it could shorten the immobility time of mice in the forced swimming test and tail suspending test. The aim… read more here.

Keywords: imbalance; hippocampus; pfc; copine ... See more keywords