Copolyelectrolyte-Based Nanocapsules for Oral Monoclonal Antibody Therapy: A Mesoscale Modeling Survey.
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DOI: 10.1021/acs.biomac.2c00699
Abstract: Antibody therapy generally requires parenteral injection to attain the required bioavailability and pharmacokinetics, but improved formulations may slow enzymatic degradation of the antibody in the gastrointestinal tract, permitting the use of noninvasive oral delivery. Rationally… read more here.
Keywords: based nanocapsules; antibody therapy; copolyelectrolyte based; antibody ... See more keywords