Engineered Protein Copolymers for Heparin Neutralization and Detection
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01464
Abstract: Heparin is a widely applied anticoagulant agent. However, in clinical practice, it is of vital importance to reverse its anticoagulant effect to restore the blood-clotting cascade and circumvent side effects. Inspired by protein cages that… read more here.
Keywords: protein copolymers; engineered protein; heparin neutralization; detection ... See more keywords
Sulfonated Copolymers as Heparin-Mimicking Stabilizer of Fibroblast Growth Factor: Size, Architecture, and Monomer Distribution Effects.
Sign Up to like & getrecommendations! Published in 2019 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b01451
Abstract: Fibroblast growth factors (FGF) are involved in a wide range of biological processes such as cell proliferation and differentiation. In living organisms, the binding of FGF to its receptors are mediated through electrostatic interactions between… read more here.
Keywords: sulfonated copolymers; heparin mimicking; copolymers heparin; fibroblast growth ... See more keywords