Copper-catalysed formylation of amines using methanol as the C1 source.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.201903266
Abstract: Cu/TEMPO as catalytic system is known for the selective transformation of alcohol to aldehyde as well as the simultaneous coupling of alcohol and amines to imines under oxidative conditions. Herein we demonstrate for the first… read more here.
Keywords: formylation; formylation amines; catalysed formylation; methanol ... See more keywords
Copper(I)-catalysed aerobic oxidative selective cleavage of C C bond with DMAP: Facile access to N-substituted benzamides
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153199
Abstract: Abstract A base/DMAP system for efficient oxidative cleavage of C(CO)–C(alkyl) bond to generate N-substituted benzamides has been developed in the presence of copper(I) chloride. The usage of inexpensive copper catalyst, broad substrate scope, mild conditions… read more here.
Keywords: substituted benzamides; cleavage; copper catalysed; dmap ... See more keywords
Photoinduced copper-catalysed asymmetric amidation via ligand cooperativity.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03730-w
Abstract: The substitution of an alkyl electrophile by a nucleophile is a foundational reaction in organic chemistry that enables the efficient and convergent synthesis of organic molecules. Whereas substantial progress has been reported in recent years… read more here.
Keywords: catalysed asymmetric; copper; asymmetric amidation; substitution ... See more keywords
Copper(i)-catalysed transfer hydrogenations with ammonia borane.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c6cc09067b
Abstract: Highly Z-selective alkyne transfer semihydrogenations and conjugate transfer hydrogenations of enoates can be effected by employing a readily available and air-stable copper(i)/N-heterocyclic carbene (NHC) complex, [IPrCuOH]. As an easy to handle and potentially recyclable H2… read more here.
Keywords: copper catalysed; ammonia borane; transfer; transfer hydrogenations ... See more keywords
Accelerated multi-reagent copper catalysed coupling reactions in micro droplets and thin films
Sign Up to like & getrecommendations! Published in 2018 at "Reaction Chemistry and Engineering"
DOI: 10.1039/c8re00002f
Abstract: Electrospray (ES) and paper spray (PS) mass spectrometry were used to create confined liquid volumes in which accelerated air and water sensitive, heterogeneous, copper catalysed C–O and C–N coupling reactions occur. Significant reaction acceleration was… read more here.
Keywords: chemistry; accelerated multi; copper catalysed; coupling reactions ... See more keywords
Copper-catalysed Csp3-Csp cross-couplings between cyclobutanone oxime esters and terminal alkynes induced by visible light.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc00988a
Abstract: A novel transformation for the construction of Csp3-Csp bonds was achieved via a photo-induced copper-catalysed C-C bond cleavage. This approach was applied to prepare a series of highly functionalized alkynyl nitriles using readily available cyclobutanones… read more here.
Keywords: copper catalysed; copper; terminal alkynes; csp3 csp ... See more keywords
Copper-catalysed ortho-selective C-H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc04495d
Abstract: Herein, we reported the first copper-catalyzed highly efficient C(sp2)-H functionalization of unprotected naphthols and phenols with α-aryl-α-diazoesters. In this transformation, CuCl2 efficiently promoted the highly chemo- and site-selective C-H bond functionalization under mild conditions, furnishing… read more here.
Keywords: functionalization; bond functionalization; aryl diazoesters; selective bond ... See more keywords
Photoinduced, copper-catalysed direct perfluoroalkylation of heteroarenes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02146c
Abstract: An efficient and general process is reported for the photoinduced, copper-catalysed direct perfluoroalkylation of C-H bonds in a broad range of heteroarenes with commercially available perfluoroalkyl iodides. This redox neutral process is simply based on… read more here.
Keywords: direct perfluoroalkylation; copper catalysed; photoinduced copper; catalysed direct ... See more keywords
Experimental and computational insights into the mechanism of the copper(I)-catalysed sulfonylative Suzuki-Miyaura reaction
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d3sc01337e
Abstract: A mechanistic study into the copper(I)-catalysed sulfonylative Suzuki-Miyaura reaction, incorporating sulfur dioxide, is described. Utilising spectroscopic and computational techniques, an exploration into the individual components of the competing catalytic cycles... read more here.
Keywords: miyaura reaction; catalysed sulfonylative; suzuki miyaura; copper catalysed ... See more keywords
Theoretical insights into the antiradical activity and copper-catalysed oxidative damage of mexidol in the physiological environment
Sign Up to like & getrecommendations! Published in 2022 at "Royal Society Open Science"
DOI: 10.1098/rsos.211239
Abstract: Mexidol (MD, 2-ethyl-6-methyl-3-hydroxypyridine) is a registered therapeutic agent for the treatment of anxiety disorders. The chemical structure suggests that MD may also act as an antioxidant. In this study, the hydroperoxyl radical scavenging activity of… read more here.
Keywords: oxidative damage; catalysed oxidative; copper catalysed; activity ... See more keywords