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Published in 2019 at "Cancers"
DOI: 10.3390/cancers11050659
Abstract: High affinity copper binding to mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) allosterically promotes the kinase activity of MEK1/2 on extracellular signal regulated kinases 1 and 2 (ERK1/2). Consequently, copper-dependent activation of…
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Keywords:
copper chelation;
kinase;
effects copper;
colon ... See more keywords