A copper-dependent compound restores ampicillin sensitivity in multidrug-resistant Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65978-y
Abstract: Multi-drug resistant Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), has become a worldwide, major health care problem. While initially restricted to clinical settings, drug resistant S. aureus is now one of the key causative agents… read more here.
Keywords: staphylococcus aureus; aureus; resistant staphylococcus; copper ... See more keywords
Novel dithiocarbamate derivatives are effective copper-dependent antimicrobials against Streptococcal species
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1099330
Abstract: Despite the availability of several vaccines against multiple disease-causing strains of Streptococcus pneumoniae, the rise of antimicrobial resistance and pneumococcal disease caused by strains not covered by the vaccine creates a need for developing novel… read more here.
Keywords: copper dependent; compound; copper; dependent antimicrobials ... See more keywords
Copper-Dependent Kinases and Their Role in Cancer Inception, Progression and Metastasis
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DOI: 10.3390/biom12101520
Abstract: In recent years, copper function has been expanded beyond its consolidated role as a cofactor of enzyme catalysis. Recent papers have demonstrated a new dynamic role for copper in the regulation of cell signaling pathways… read more here.
Keywords: growth dissemination; copper dependent; copper; role ... See more keywords
ATP7A-Regulated Enzyme Metalation and Trafficking in the Menkes Disease Puzzle
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DOI: 10.3390/biomedicines9040391
Abstract: Copper is vital for numerous cellular functions affecting all tissues and organ systems in the body. The copper pump, ATP7A is critical for whole-body, cellular, and subcellular copper homeostasis, and dysfunction due to genetic defects… read more here.
Keywords: menkes disease; enzyme metalation; copper; copper dependent ... See more keywords