Copper diisobutyl-t-butoxyaluminum hydride: A novel reagent for chemoselective reduction of tertiary amides over esters
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DOI: 10.1016/j.tetlet.2018.04.082
Abstract: Abstract We demonstrate that copper diisobutyl-t-butoxyaluminum hydride, readily prepared from lithium diisobutyl-t-butoxyaluminum hydride and CuI, effectively and chemoselectively reduces tertiary amides over esters at ambient temperature, affording the corresponding aldehydes in excellent yields. read more here.
Keywords: butoxyaluminum hydride; copper diisobutyl; diisobutyl butoxyaluminum; tertiary amides ... See more keywords