A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker
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DOI: 10.1186/s12885-021-08242-4
Abstract: Background Disulfiram and metals inactivate key oncoproteins resulting in anti-neoplastic activity. The goal of this study was to determine the maximum tolerated dose of copper when administered with disulfiram in patients with advanced solid tumors… read more here.
Keywords: copper gluconate; solid tumors; glutathionylation; copper ... See more keywords