Selective Targeting of Cancer Cells by Copper Ionophores: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.841814
Abstract: Conventional cancer therapies suffer from severe off-target effects because most of them target critical facets of cells that are generally shared by all rapidly proliferating cells. The development of new therapeutic agents should aim to… read more here.
Keywords: cancer; cells copper; targeting cancer; cancer cells ... See more keywords
Copper Ionophores as Novel Antiobesity Therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25214957
Abstract: The therapeutic utility of the copper ionophore disulfiram was investigated in a diet-induced obesity mouse model (C57BL/6J background), both through administration in feed (0.05 to 1% (w/w)) and via oral gavage (150 mg/kg) for up… read more here.
Keywords: hepatic copper; disulfiram; copper; copper ionophores ... See more keywords