Insights into the Active Site of Coproheme Decarboxylase from Listeria monocytogenes
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00186
Abstract: Coproheme decarboxylases (ChdC) catalyze the hydrogen peroxide-mediated conversion of coproheme to heme b. This work compares the structure and function of wild-type (WT) coproheme decarboxylase from Listeria monocytogenes and its M149A, Q187A, and M149A/Q187A mutants.… read more here.
Keywords: coproheme; coproheme decarboxylase; decarboxylase listeria; listeria monocytogenes ... See more keywords
Reorienting Mechanism of Harderoheme in Coproheme Decarboxylase—A Computational Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052564
Abstract: Coproheme decarboxylase (ChdC) is an important enzyme in the coproporphyrin-dependent pathway (CPD) of Gram-positive bacteria that decarboxylates coproheme on two propionates at position 2 and position 4 sequentially to generate heme b by using H2O2… read more here.
Keywords: coproheme decarboxylase; mechanism harderoheme; mechanism; reorienting mechanism ... See more keywords