Immunogenicity and efficacy following sequential parenterally-administered doses of Salmonella Enteritidis COPS:FliC glycoconjugates in infant and adult mice
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DOI: 10.1371/journal.pntd.0006522
Abstract: In sub-Saharan Africa, invasive nontyphoidal Salmonella (iNTS) infections with serovars S. Enteritidis, S. Typhimurium and I 4,[5],12:i:- are widespread in children < 5 years old. Development of an efficacious vaccine would provide an important public… read more here.
Keywords: infant adult; cops flic; adult mice; enteritidis cops ... See more keywords
Maternal Antibodies Elicited by Immunization With an O- Polysaccharide Glycoconjugate Vaccine Protect Infant Mice Against Lethal Salmonella Typhimurium Infection
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DOI: 10.3389/fimmu.2019.02124
Abstract: Non-typhoidal Salmonella (NTS) are a leading cause of pediatric invasive bacterial infections in sub-Saharan Africa with high associated case fatality rates in children under 5 years old. We have developed glycoconjugate vaccines consisting of the… read more here.
Keywords: cops flic; salmonella; maternal antibodies; infant mice ... See more keywords