Scutellariae radix and coptidis rhizoma ameliorate glycolipid metabolism of type 2 diabetic rats by modulating gut microbiota and its metabolites
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DOI: 10.1007/s00253-019-10174-w
Abstract: Scutellariae radix ( Scutellaria baicalensis Georgi, SR) and coptidis rhizoma ( Coptis chinensis Franch, CR) are both widely used traditional Chinese medicines and have been used together to treat T2DM with synergistic effects in the… read more here.
Keywords: microbiota; microbiota metabolites; coptidis rhizoma; gut microbiota ... See more keywords
Identification of anti-inflammatory constituents in Phellodendri Cortex and Coptidis Rhizoma by monitoring the suppression of nitric oxide production
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-017-1107-4
Abstract: Phellodendri Cortex (Obaku in Japanese) and Coptidis Rhizoma (Oren), both of which contain berberine, have been used to prepare the kampo formula orengedokuto to treat inflammatory diseases, including dermatitis, gastric ulcers, and gastritis. These drugs… read more here.
Keywords: anti inflammatory; coptidis rhizoma; phellodendri cortex; production ... See more keywords
Preparation and adsorption characteristics of rosin-based polymer microspheres for berberine hydrochloride and separation of total alkaloids from coptidis rhizoma
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.123707
Abstract: Abstract Coptidis rhizoma, the dried rhizome of the plant Coptis, is a source of potentially valuable alkaloids, including berberine hydrochloride (BBH). However, extraction of these compounds is challenging, and existing resins for adsorption-based separation and… read more here.
Keywords: adsorption; rosin based; separation; coptidis rhizoma ... See more keywords
Inhibitory effects of Coptidis Rhizoma on the intestinal absorption and metabolism of Scutellariae Radix.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.113785
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The Scutellariae Radix (SR) and Coptidis Rhizoma (CR) herb couple is widely used in traditional Chinese medicine prescriptions for treatment of diabetes mellitus due to its interaction and synergistic effect compared to either… read more here.
Keywords: absorption; metabolism; treated group; coptidis rhizoma ... See more keywords
Rapid and simultaneous determination of moisture and berberine content in Coptidis Rhizoma and Phellodendri Chinensis Cortex by near-infrared spectroscopy and chemometrics
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Innovative Optical Health Sciences"
DOI: 10.1142/s1793545820500066
Abstract: Coptidis Rhizoma (Chinese: Huanglian) and Phellodendri Chinensis Cortex (Chinese: Huangbo) are widely used Traditional Chinese Medicine, and often used in combination because of their similar pharmacological effects in clinical practice. However, the quality control methods… read more here.
Keywords: moisture; content; phellodendri chinensis; coptidis rhizoma ... See more keywords
Current Advances in Coptidis Rhizoma for Gastrointestinal and Other Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.775084
Abstract: Cancer is a serious disease with an increasing number of reported cases and high mortality worldwide. Gastrointestinal cancer defines a group of cancers in the digestive system, e.g., liver cancer, colorectal cancer, and gastric cancer.… read more here.
Keywords: gastrointestinal cancer; pharmacology; coptidis rhizoma; rhizoma ... See more keywords
Therapeutic targets and pharmacological mechanisms of Coptidis Rhizoma against ulcerative colitis: Findings of system pharmacology and bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1037856
Abstract: Evidence of the advantages of Coptidis Rhizoma (CR) for the treatment of ulcerative colitis (UC) is accumulating. However, research revealing the targets and molecular mechanisms of CR against UC is scarce. In this research, a… read more here.
Keywords: bioinformatics analysis; pharmacology; key phytochemicals; coptidis rhizoma ... See more keywords
Coptidis Rhizoma Suppresses Metastatic Behavior by Inhibiting TGF-β-Mediated Epithelial-Mesenchymal Transition in 5-FU-Resistant HCT116 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.909331
Abstract: Colorectal cancer (CRC) is the second most lethal malignancy worldwide. The high mortality rate of CRC is largely due to cancer metastasis. Recently, suppressing epithelial-to-mesenchymal transition (EMT) has been considered a promising strategy for treating… read more here.
Keywords: tgf; coptidis rhizoma; rhizoma; hct116 cells ... See more keywords
Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24244567
Abstract: Alkaloids having acetylcholinesterase (AChE) inhibitory activity are commonly found in traditional Chinese medicine (TCM); for example, berberine from Coptis chinensis, galantamine from Lycoris radiata, and huperzine A from Huperzia serrata. In practice of TCM, Stephaniae… read more here.
Keywords: tetrandrae radix; inhibition; stephaniae tetrandrae; coptidis rhizoma ... See more keywords
Development and Validation of an UPLC-MS/MS Method for Pharmacokinetic Comparison of Five Alkaloids from JinQi Jiangtang Tablets and Its Monarch Drug Coptidis Rhizoma
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DOI: 10.3390/pharmaceutics10010004
Abstract: JinQi Jiangtang (JQJT) tablets, a Chinese patent medicine approved by the State Food and Drug Administration, are composed of Coptidis Rhizoma, Astragali Radix, and Lonicerae Japonicae Flos, and have a significant effect on diabetes. Coptidis… read more here.
Keywords: jinqi jiangtang; drug; five alkaloids; coptidis rhizoma ... See more keywords