Cholinesterase inhibitory alkaloids from the rhizomes of Coptis chinensis.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.01.038
Abstract: Coptis chinensis has been used as a medicinal herb in traditional oriental medicine. In this study, chemical investigation of a water extract of C. chinensis identified two new quaternary protoberberines (1, 2), a new tricyclic… read more here.
Keywords: inhibitory alkaloids; inhibition; cholinesterase inhibitory; coptis chinensis ... See more keywords
AChE inhibitory alkaloids from Coptis chinensis.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104464
Abstract: Coptis chinensis is a widely used traditional Chinese herbal medicine. In this work, 6 new alkaloids (coptisine A-F, 1-6) and 26 known alkaloids (7-32) were isolated from the chloroform extract of the rhizomes of C.… read more here.
Keywords: inhibitory alkaloids; ache inhibitory; coptis chinensis; alkaloids coptis ... See more keywords
Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis
Sign Up to like & getrecommendations! Published in 2022 at "Scientia Horticulturae"
DOI: 10.1016/j.scienta.2021.110585
Abstract: Abstract Berberine is the primary medicinal component of Coptis chinensis, a perennial herb in Ranunculaceae. It has pharmacological effects, such as clearing away heat and dampness, purging fire and detoxifying, and resisting oxidation, and is… read more here.
Keywords: biosynthesis; comparative transcriptome; analysis; coptis chinensis ... See more keywords
Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23611-0
Abstract: Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales, represents an important early-diverging eudicot lineage with diverse medicinal applications. Here, we present a high-quality chromosome-scale genome assembly and annotation of C. chinensis. Phylogenetic and… read more here.
Keywords: type alkaloids; protoberberine type; coptis chinensis; chinensis ... See more keywords
A new integrated method of magnetic separation of isoquinoline alkaloids from Coptis chinensis based on their magnetized derivatives and key physical properties
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/d0nj00731e
Abstract: For the first time, a new magnetic separation strategy for alkaloids from Coptis chinensis was developed in this study. For basic research, physical properties including thermal properties, solubility and magnetic properties of six Fe-containing magnetic… read more here.
Keywords: physical properties; coptis chinensis; magnetic separation; alkaloids coptis ... See more keywords
First report of Ilyonectria robusta causing root rot on Coptis chinensis in Chongqing, China.
Sign Up to like & getrecommendations! Published in 2023 at "Plant disease"
DOI: 10.1094/pdis-11-22-2623-pdn
Abstract: Coptis chinensis belongs to the Ranunculaceae family and is a widely used traditional Chinese herb. Chongqing Municipality produces >60% of China's production. Root rot seriously reduced yield and quality (Mei et al. 2021). In May… read more here.
Keywords: root; coptis chinensis; root rot; ilyonectria robusta ... See more keywords
Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14725
Abstract: Coptisine is a natural small‐molecular compound extracted from Coptis chinensis (CC) with a history of using for thousands of years. This work aimed at summarizing coptisine's activity and providing advice for its clinical use. We… read more here.
Keywords: coptisine coptis; coptis chinensis; exerts diverse; chinensis exerts ... See more keywords
Effective Extraction of Palmatine and Berberine from Coptis chinensis by Deep Eutectic Solvents-Based Ultrasound-Assisted Extraction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Analytical Methods in Chemistry"
DOI: 10.1155/2021/9970338
Abstract: The effective components of Coptis chinensis were extracted by ultrasound-assisted technology, and the contents of palmatine and berberine were used as indexes by using Coptis chinensis as raw material and eutectic solvent as extractant. In… read more here.
Keywords: palmatine berberine; extraction; coptis chinensis;
The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats
Sign Up to like & getrecommendations! Published in 2018 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s171025
Abstract: Background Coptis chinensis Franch is extensively used in traditional Chinese medicine to treat diabetes and dementia. Alkaloids are the main active ingredients of C. chinensis. Purpose This study was designed to probe the effects and… read more here.
Keywords: cognitive deficits; coptis chinensis; type diabetic; diabetic rats ... See more keywords
Uncovering the Potential Mechanisms of Coptis chinensis Franch. for Serious Mental Illness by Network Pharmacology and Pharmacology-Based Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s342028
Abstract: Background Serious mental illness is a disease with complex etiological factors that requires multiple interventions within a holistic disease system. With heat-clearing and detoxifying effects, Coptis chinensis Franch. is mainly used to treat serious mental… read more here.
Keywords: pharmacology; serious mental; chinensis franch; coptis chinensis ... See more keywords
Biosynthesis, characterization, and anticancer effect of plant-mediated silver nanoparticles using Coptis chinensis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s188235
Abstract: Background Tremendous growth in nanotechnology has opened up new frontiers in fundamental and applied aspects, including the synthesis of nanoscale matter and understanding/utilizing its exotic physicochemical and optoelectronic properties. Green-synthesis methods employing either biological microorganisms… read more here.
Keywords: coptis chinensis; silver nanoparticles; synthesis; plant ... See more keywords