Assembly and Characterization of Biocompatible Coenzyme Q10 -Enriched Lipid Nanoparticles.
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DOI: 10.1002/lipd.12218
Abstract: Coenzyme Q10 (CoQ10 ) is a strongly hydrophobic lipid that functions in the electron transport chain and as an antioxidant. CoQ10 was conferred with aqueous solubility by incorporation into nanoparticles containing phosphatidylcholine (PtdCho) and apolipoprotein… read more here.
Keywords: coenzyme q10; assembly characterization; coq10; lipid nanoparticles ... See more keywords
Targeted Treatment of Age-Related Fibromyalgia with Supplemental Coenzyme Q10.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55035-6_5
Abstract: Fibromyalgia is a common chronic pain condition of unknown aetiology, although mitochondrial dysfunction, oxidative stress, and inflammation have been implicated in the pathophysiology of this disorder. Treatment generally involves physiotherapy, anticonvulsants, and antidepressant therapy; however,… read more here.
Keywords: coenzyme q10; treatment; targeted treatment; coq10 ... See more keywords
The influence of vinpocetine alone or in combination with Epigallocatechin-3-gallate, Coenzyme COQ10, Vitamin E and Selenium as a potential neuroprotective combination against aluminium-induced Alzheimer's disease in Wistar Albino Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2021.104557
Abstract: Alzheimer's disease (AD) is one of such diseases that represent the most prominent cause of dementia in elderly people. To explore the possible neuroprotective effect as well as mechanism of action of Vinpocetine either alone… read more here.
Keywords: combination; alone combination; vinpocetine; alzheimer disease ... See more keywords
Enhanced synthesis of Coenzyme Q10 by reducing the competitive production of carotenoids in Rhodobacter sphaeroides
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2017.03.019
Abstract: Abstract In Rhodobacter sphaeroides, synthesis of coenzyme Q10 (CoQ10) shares the same precursor geranylgeranyl diphosphate (GGPP) with carotenoids. Therefore, suppression of carotenoids synthesis is supposed to pose positive effects on accumulation of CoQ10. In this… read more here.
Keywords: synthesis coenzyme; production; coq10; coenzyme q10 ... See more keywords
Coenzyme Q10 ameliorates BPA-induced apoptosis by regulating autophagy-related lysosomal pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112450
Abstract: Bisphenol A (BPA) is a widely distributed environmental endocrine disruptor. The accumulation of BPA has been proved that produce various toxic effects both on human and animals. However, the strategies to reduce the damage of… read more here.
Keywords: bpa; apoptosis; q10 ameliorates; coq10 ... See more keywords
Coenzyme Q 10 supplementation: A potential therapeutic option for the treatment of intrahepatic cholestasis of pregnancy.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173270
Abstract: Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy specific liver disease characterized by pruritus, elevated serum bile acids and abnormal liver function that may be associated with severe adverse pregnancy outcomes. We previously reported that… read more here.
Keywords: supplementation; pregnancy; cholestasis pregnancy; coq10 ... See more keywords
New electrochemical sensor based on CoQ10 and cyclodextrin complexes for the detection of oxidative stress initiators
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DOI: 10.1016/j.electacta.2019.02.060
Abstract: Abstract The development of coenzyme Q10 (CoQ10) based electrochemical sensor for the detection of oxidative stress initiators is described for the first time. The sensor relies on CoQ10 redox properties. CoQ10 was immobilized at the… read more here.
Keywords: spectroscopy; detection oxidative; electrochemical sensor; coq10 ... See more keywords
Dendrimer-like glucan nanoparticulate system improves the solubility and cellular antioxidant activity of coenzyme Q10.
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DOI: 10.1016/j.foodchem.2020.127510
Abstract: Aqueous coenzyme Q10 (CoQ10) dispersions were prepared using sugary maize dendrimer-like glucan (SMDG) with solid-dispersion treatment. After measuring solubility, recovery rate and loading rate, the initial weight ratio of CoQ10:SMDG was optimized to be 1:27,… read more here.
Keywords: coq10 smdg; like glucan; coq10; activity ... See more keywords
Placental and mitochondrial Q10 content after CoQ10 supplementation during pregnancy
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.259
Abstract: Pre-eclampsia is a common disorder of human pregnancy (about 7% of all pregnancies) in which the normal hemodynamic response to pregnancy is compromised. In 2009, we demonstrated that supplementation with CoQ10 reduces significantly the risk… read more here.
Keywords: supplementation; placental mitochondrial; pregnancy; coq10 ... See more keywords
Ubiquinol supplemenetation in elderly patients undergoing aortic valve replacement: Biochemical and clinical effects
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DOI: 10.1016/j.freeradbiomed.2017.04.314
Abstract: There is a steady rise in the mean age of patients affected by heart disease undergoing cardiac surgery. However senescent myocardium has reduced tolerance to ischemic stress and there are clear indications about age-associated deficit… read more here.
Keywords: aortic valve; patients undergoing; coq10; valve replacement ... See more keywords
Comparison on the Roles of COQ3 and COQ7 Proteins in Maintaining Coenzyme Q10 Levels, the Stability of Other COQ Proteins, and Mitochondrial Functions in Human Cells
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.264
Abstract: Coenzyme Q (CoQ) is a lipid-soluble antioxidant, with the oxidized (ubiquinone) and the reduced (ubiquinol) forms, and also an electron carrier for the electron transport chain. CoQ6 is synthesized by at least nine proteins (Coq1--9),… read more here.
Keywords: coq7 knockdown; coq3 coq7; coq proteins; coq10 ... See more keywords