Abstract 5184: N-CoR2 epigenetically regulates adhesion-dependent branching morphogenesis and its loss correlates with malignant progression of the mammary gland
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-5184
Abstract: Branching morphogenesis depends upon extracellular matrix remodeling and dynamic cell-cell and cell-extracellular matrix interactions, although how this developmental program is coordinated remains unclear. Expression profiling of mammary tissue at different stages of branching morphogenesis combined… read more here.
Keywords: branching morphogenesis; adhesion; mammary gland; cor2 ... See more keywords
Abstract A49: A dual blockade of N-CoR2- and immune checkpoints induces complete remissions in treatment-refractory tumors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm18-a49
Abstract: Background: The majority of human malignant tumors are resistant or only partially respond to conventional chemotherapy (C/T) or immunotherapy (I/T) such as immune checkpoint inhibitors (ICIs). Irrespective of the treatments, efficient tumor-cell killing requires amplification… read more here.
Keywords: checkpoint; treatment; immunology; cor2 ... See more keywords