Early vs Late Surgical Decompression for Central Cord Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA surgery"
DOI: 10.1001/jamasurg.2022.4454
Abstract: Importance The optimal clinical management of central cord syndrome (CCS) remains unclear; yet this is becoming an increasingly relevant public health problem in the face of an aging population. Objective To provide a head-to-head comparison… read more here.
Keywords: cord; surgery; motor; motor score ... See more keywords
The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.12144
Abstract: Abstract Introduction The spinal cord is poorly visualized on CT images but is well visualized in MRI images. However, implants used for spinal stabilization can produce artifacts on the MRI images which can interfere with… read more here.
Keywords: myelography; cord; post myelogram; spinal cord ... See more keywords
Diffusion tensor imaging metrics in diagnosis of HTLV‐1‐associated myelopathy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51521
Abstract: OBJECTIVE In the diagnosis of HTLV-1-associated myelopathy (HAM), while magnetic resonance imaging (MRI) is essential to exclude other diseases, its power is limited regarding HAM diagnosis, as only 30% of affected patients present with spinal… read more here.
Keywords: thoracic; diagnosis htlv; cord; spinal cord ... See more keywords
NSCs Migration Promoted and Drug Delivered Exosomes-Collagen Scaffold via a Bio-Specific Peptide for One-Step Spinal Cord Injury Repair.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001896
Abstract: Spinal cord injury (SCI) is plaguing medical professionals globally due to the complexity of injury progression. Based on tissue engineering technology, there recently emerges a promising way by integrating drugs with suitable scaffold biomaterials to… read more here.
Keywords: exosomes collagen; cord; migration; collagen scaffold ... See more keywords
Defined Alginate Hydrogels Support Spinal Cord Organoid Derivation, Maturation, and Modeling of Spinal Cord Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202342
Abstract: In the process of generating organoids, basement membrane extracts or Matrigel are often used to encapsulate cells but they are poorly defined and contribute to reproducibility issues. While defined hydrogels are increasingly used for organoid… read more here.
Keywords: cord; cord organoid; alginate hydrogels; organoid derivation ... See more keywords
GDNF‐Loaded Polydopamine Nanoparticles‐Based Anisotropic Scaffolds Promote Spinal Cord Repair by Modulating Inhibitory Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202377
Abstract: Spinal cord injury (SCI) is a devastating injury that causes permanent loss of sensation and motor function. SCI repair is a significant challenge due to the limited regenerating ability of adult neurons and the complex… read more here.
Keywords: cord; based anisotropic; cord repair; gdnf loaded ... See more keywords
A Modular Assembly of Spinal Cord–Like Tissue Allows Targeted Tissue Repair in the Transected Spinal Cord
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201800261
Abstract: Abstract Tissue engineering–based neural construction holds promise in providing organoids with defined differentiation and therapeutic potentials. Here, a bioengineered transplantable spinal cord–like tissue (SCLT) is assembled in vitro by simulating the white matter and gray… read more here.
Keywords: cord; spinal cord; like tissue; cord like ... See more keywords
A Subdural Bioelectronic Implant to Record Electrical Activity from the Spinal Cord in Freely Moving Rats
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105913
Abstract: Bioelectronic devices have found use at the interface with neural tissue to investigate and treat nervous system disorders. Here, the development and characterization of a very thin flexible bioelectronic implant inserted along the thoracic spinal… read more here.
Keywords: cord; freely moving; bioelectronic implant; activity ... See more keywords
Sex‐specific characteristics of cells expressing the cannabinoid 1 receptor in the dorsal horn of the lumbar spinal cord
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25342
Abstract: It is becoming increasingly clear that robust sex differences exist in the processing of acute and chronic pain in both rodents and humans. However, the underlying mechanism has not been well characterized. The dorsal horn… read more here.
Keywords: cord; lumbar; sex; spinal cord ... See more keywords
Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival.
Sign Up to like & getrecommendations! Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22052
Abstract: This study aimed to investigate the therapeutic effects of cinepazide maleate (CM) on spinal cord injury (SCI) in rats, thereby providing an experimental basis for the use of CM as a preventative and therapeutic strategy… read more here.
Keywords: cord; inflammation; cinepazide maleate; treatment ... See more keywords
E6020, a synthetic TLR4 agonist, accelerates myelin debris clearance, Schwann cell infiltration, and remyelination in the rat spinal cord
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23132
Abstract: Oligodendrocyte progenitor cells (OPCs) are present throughout the adult brain and spinal cord and can replace oligodendrocytes lost to injury, aging, or disease. Their differentiation, however, is inhibited by myelin debris, making clearance of this… read more here.
Keywords: synthetic tlr4; cord; myelin debris; tlr4 agonist ... See more keywords