Human umbilical cord mesenchymal stem cells derived exosomes exert antiapoptosis effect via activating PI3K/Akt/mTOR pathway on H9C2 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28705
Abstract: In recent years, as an alternative to stem cell therapy for cardiovascular diseases (CVD), exsomes have attracted wide attention among researchers. The present study aimed to investigate the role of human umbilical cord mesenchymal stem… read more here.
Keywords: umbilical cord; human umbilical; stem; stem cells ... See more keywords
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200204
Abstract: Exosomes derived from mesenchymal stem cells (MSCs) have been used for cancer treatment, however, an in‐depth analysis of the exosomal proteomes is lacking. In this manuscript, we use the diaPASEF (parallel accumulation serial fragmentation combined… read more here.
Keywords: umbilical cord; cord mesenchymal; analysis; mesenchymal stem ... See more keywords
Conditioned medium from umbilical cord mesenchymal stem cells improves nasal mucosa damage by radiation
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Letters"
DOI: 10.1007/s10529-018-2553-0
Abstract: ObjectivesTo explore therapeutic effects of conditioned medium from human umbilical cord mesenchymal stem cells (hUC-MSCs) on nasal mucosa radiation damage both in vivo and in vitro.ResultsThe mucus cilia clearance time (7 and 30 days), degree of… read more here.
Keywords: conditioned medium; nasal mucosa; umbilical cord; damage ... See more keywords
Efficacy and mechanisms underlying the effects of allogeneic umbilical cord mesenchymal stem cell transplantation on acute radiation injury in tree shrews
Sign Up to like & getrecommendations! Published in 2018 at "Cytotechnology"
DOI: 10.1007/s10616-018-0239-z
Abstract: Umbilical cord mesenchymal stem cells (UC-MSCs) exert strong immunomodulatory effects and can repair organs. However, their roles in radiation injury remain unclear. We show that in tree shrews with acute radiation injury, injected UC-MSCs significantly… read more here.
Keywords: radiation injury; umbilical cord; acute radiation; injury ... See more keywords
Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of stabilized fracture
Sign Up to like & getrecommendations! Published in 2019 at "Cell Proliferation"
DOI: 10.1111/cpr.12570
Abstract: Exosomes, as important players in intercellular communication due to their ability to transfer certain molecules to target cells, are believed to take similar effects in promoting bone regeneration with their derived stem cells. Studies have… read more here.
Keywords: angiogenesis; umbilical cord; fracture; stem cells ... See more keywords
Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-020-00708-0
Abstract: Background Umbilical cord mesenchymal stem cell (HUCMSC)-based therapies were previously utilised for cartilage regeneration because of the chondrogenic potential of MSCs. However, chondrogenic differentiation of HUCMSCs is limited by the administration of growth factors like… read more here.
Keywords: umbilical cord; differentiation; chondrogenic differentiation; stem ... See more keywords
Effects of umbilical cord mesenchymal stem cells on expression of CYR61, FSH and AMH in mice with premature ovarian failure.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2021.67.5.41
Abstract: The aim of this study was to objective to investigate the effects of umbilical cord mesenchymal stem cells on the expression of CYR61, FSH and AMH in mice with premature ovarian failure. For this purpose,… read more here.
Keywords: umbilical cord; group group; cord mesenchymal; group ... See more keywords
Therapeutic effects of human umbilical cord mesenchymal stem cell on sepsis-associated encephalopathy in mice by regulating PI3K/AKT pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2101038
Abstract: Sepsis-associated encephalopathy is a common brain diseases, presenting severe diffuse brain dysfunction. The umbilical cord mesenchymal stem cells have been reported to have protective role for treating diseases, while its role in sepsis-associated encephalopathy remained… read more here.
Keywords: umbilical cord; associated encephalopathy; cord mesenchymal; mesenchymal stem ... See more keywords
Immunological characteristics of human umbilical cord mesenchymal stem cells after hepatogenic differentiation.
Sign Up to like & getrecommendations! Published in 2022 at "Bio-medical materials and engineering"
DOI: 10.3233/bme-211331
Abstract: BACKGROUND Acute liver failure is one of the most intractable clinical problems. The use of bioartificial livers may solve donor shortage problems. Human umbilical cord mesenchymal stem cells (hUCMSCs) are an excellent seed cell choice… read more here.
Keywords: umbilical cord; cord mesenchymal; mesenchymal stem; human umbilical ... See more keywords
Circular RNA Involvement in the Protective Effect of Human Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Against Hypoxia/Reoxygenation Injury in Cardiac Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.626878
Abstract: Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles (HuMSC-EVs) can repair damaged tissues. The expression profile of circular RNAs (circRNAs) provides valuable insights into the regulation of the repair process and the exploration of the… read more here.
Keywords: mesenchymal stromal; umbilical cord; humsc evs; human umbilical ... See more keywords
Pre-clinical efficacy evaluation of human umbilical cord mesenchymal stem cells for ischemic stroke
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1095469
Abstract: Objective This study explored the underlying therapeutic mechanism of human umbilical cord mesenchymal stem cells (hUCMSCs) for ischemic stroke (IS), and determined the optimal administration time windows and dose-effect relationship. Methods The levels of SDF-1α,… read more here.
Keywords: brain; umbilical cord; brain tissues; cord mesenchymal ... See more keywords