Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.
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DOI: 10.1016/j.ydbio.2017.04.002
Abstract: Sonic Hedgehog (Shh) signaling regulates the patterning of ventral spinal cord through the effector Gli family of transcription factors. Previous in vitro studies showed that an E3 ubiquitin ligase containing Speckle-type POZ protein (Spop) targets… read more here.
Keywords: cord; shh signaling; spop; cord patterning ... See more keywords