Cultured Cordyceps sinensis polysaccharides modulate intestinal mucosal immunity and gut microbiota in cyclophosphamide-treated mice.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.115957
Abstract: The present study aimed to investigate the protective effect of cultured Cordyceps sinensis polysaccharides (CSP) on cyclophosphamide (Cy)-induced intestinal mucosal immunosuppression and microbial dysbiosis in mice. Results showed that CSP stimulated cytokines secretion (IL-12, IFN-γ,… read more here.
Keywords: cultured cordyceps; gut microbiota; intestinal mucosal; cordyceps sinensis ... See more keywords
Structural characterization and chain conformation of a water-soluble β-glucan from wild Cordyceps sinensis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05340
Abstract: A water-soluble β-D-glucan was obtained from wild Cordyceps sinensis (C. sinensis) by alkali solution and ethanol precipitation. The structure characteristics were determined using high performance anion exchange chromatography coupled with pulsed amperometric detection (HPAEC-PAD), methylation… read more here.
Keywords: soluble glucan; wild cordyceps; cordyceps sinensis; water soluble ... See more keywords
Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra01470j
Abstract: Notoginsenoside R1 is a dammarane saponin in Panax notoginseng with promising cardioprotective effects. The bioactivity–structure relationship of such saponins suggested that the presence of a hydroxyl group at C25 could elevate its performance. To fulfill… read more here.
Keywords: effect; mediated biotransformation; sinensis mediated; cordyceps sinensis ... See more keywords
Three new ɑ-pyrone derivatives induced by chemical epigenetic manipulation of Penicillium herquei, an endophytic fungus isolated from Cordyceps sinensis
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DOI: 10.1080/14786419.2018.1544974
Abstract: Abstract Chemical epigenetic manipulation was applied to explore secondary metabolite of an endophytic fungus Penicillium herquei, which was obtained from the fruiting body of Cordyceps sinensis, and three previously undescribed polyketides with pyran-2-one scaffold were… read more here.
Keywords: chemical epigenetic; endophytic fungus; epigenetic manipulation; cordyceps sinensis ... See more keywords
Nucleosides and amino acids, isolated from Cordyceps sinensis, protected against cyclophosphamide-induced myelosuppression in mice
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2043307
Abstract: Abstract The material basis of Cordyceps sinensis (Berk.) Sacc has not yet been well understood and natural C. sinensis resources are very rare. The present study aimed to clarify the substance basis and compare the… read more here.
Keywords: nucleosides amino; amino acids; induced myelosuppression; myelosuppression mice ... See more keywords
Network Pharmacology and Molecular Docking Analysis Explores the Mechanisms of Cordyceps sinensis in the Treatment of Oral Lichen Planus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3156785
Abstract: Objective Oral lichen planus (OLP) is the most common potentially malignant disorder of the oral cavity. This study aimed to investigate the mechanism of action of Cordyceps sinensis in the treatment of OLP and provides… read more here.
Keywords: molecular docking; pharmacology; oral lichen; cordyceps sinensis ... See more keywords
Optimization of protein extraction and two-dimensional gel electrophoresis profiles for the identification of Cordyceps sinensis and other similar species
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DOI: 10.1371/journal.pone.0202779
Abstract: Given that Chinese materia medica (CMM) is expensive and rare, people take tremendous risk to adulterate and falsify Cordyceps sinensis with counterfeit species with similar morphological features. It is thus essential to develop new methods… read more here.
Keywords: sinensis; dimensional gel; gel electrophoresis; electrophoresis profiles ... See more keywords
Cordyceps sinensis promotes immune regulation and enhances bacteriostatic activity of PA-824 via IL-10 in Mycobacterium tuberculosis disease
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DOI: 10.1590/1414-431x20176188
Abstract: PA-824 is a novel bicyclic nitroimidazole anti-tuberculosis (TB) drug. Cordyceps sinensis (Berk.) Sacc. (CS) was proven to be a good immunomodulatory compound. This research aimed to investigate the effect of CS on PA-824 in Mycobacterium… read more here.
Keywords: cd4 cells; cordyceps sinensis; effect; tuberculosis ... See more keywords
Arsenic Species in Cordyceps sinensis and Its Potential Health Risks
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DOI: 10.3389/fphar.2019.01471
Abstract: High arsenic residues make Cordyceps sinensis a concern in China. Arsenic toxicity is related to its species. Many studies have evaluated the toxicity of total arsenic, but few have studied its species. In this study,… read more here.
Keywords: sinensis; arsenic sinensis; potential health; sinensis potential ... See more keywords
Pharmacological functions of Chinese medicinal fungus Cordyceps sinensis and related species
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DOI: 10.38212/2224-6614.2828
Abstract: Cordyceps sinensis, an entomogenous fungus used in traditional Chinese medicine, exhibits very broad biological and pharmacological actions in hepatic, renal, cardiovascular, and immunologic systems as well as anticancer activity. Pharmacological functions of Cordyceps are primarily… read more here.
Keywords: chinese medicinal; pharmacological functions; functions chinese; cordyceps sinensis ... See more keywords
Effect of fermented Cordyceps sinensis on doxorubicin-induced cardiotoxicity in rats
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.9310
Abstract: Cordyceps sinensis (CS) is a prominent medicinal herb in traditional Chinese medicine, and fermented CS is frequently used as a substitute for natural CS. Doxorubicin (DOX), an antitumor drug used in chemotherapy, is limited by… read more here.
Keywords: medicine; induced cardiotoxicity; effect fermented; cordyceps sinensis ... See more keywords