Complex Structures Made Simple – Continuous Flow Production of Core Cross‐Linked Polymeric Micelles for Paclitaxel Pro‐Drug‐Delivery
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210704
Abstract: Translating innovative nanomaterials to medical products requires efficient manufacturing techniques that enable large‐scale high‐throughput synthesis with high reproducibility. Drug carriers in medicine embrace a complex subset of tasks calling for multifunctionality. Here, the synthesisof pro‐drug‐loaded… read more here.
Keywords: pro drug; core cross; cross; continuous flow ... See more keywords
Core‐Cross‐Linked Micellar Nanoreactors for Biaryl Synthesis in Water: Influence of Topological Structures on Catalytic Activity
Sign Up to like & getrecommendations! Published in 2025 at "Macromolecular Rapid Communications"
DOI: 10.1002/marc.202500160
Abstract: Multiple block copolymers bearing PDMAEMA (poly(2‐(dimethylamino)ethyl methacrylate), PLMA (poly(lauryl methacrylate), and PAMA (poly(allyl methacrylate) segments are synthesized via RAFT (reversible addition‐fragmentation chain transfer) polymerization. Manipulating the cross‐linkage of PAMA in the specific domain of polymeric… read more here.
Keywords: micellar nanoreactors; catalytic activity; core cross; topological structures ... See more keywords
Impact of Polyethylene Glycol (PEG) Conformations on the In Vivo Fate and Drug Release Behavior of PEGylated Core-Cross-Linked Polymeric Nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00730
Abstract: In cancer chemotherapy, core-cross-linked particles (CCPs) are a promising drug carrier due to their high structural stability in an in vivo environment, resulting in improved tumor delivery. A biocompatible polymer of polyethylene glycol (PEG) is… read more here.
Keywords: core; cross linked; polyethylene glycol; core cross ... See more keywords
Nanoscale Investigation of Elasticity Changes and Augmented Rigidity of Block Copolymer Micelles Induced by Reversible Core-Cross-Linking
Sign Up to like & getrecommendations! Published in 2025 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.5c04826
Abstract: Drug-delivery systems have attracted considerable attention due to their potential to increase the bioavailability of certain drugs and mitigate side effects by enabling targeted drug release. Reversibly core-cross-linked block copolymer micelles providing a hydrophilic and… read more here.
Keywords: block copolymer; copolymer micelles; drug; core cross ... See more keywords
Octreotide-Conjugated Core-Cross-Linked Micelles with pH/Redox Responsivity Loaded with Etoposide for Neuroendocrine Neoplasms Therapy and Bioimaging with Photoquenching Resistance.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b01827
Abstract: The study of multifunctional polymer micelles combined with chemotherapy due to reduced systemic toxicity and enhanced efficacy has attracted intensive attention. Herein, a multifunctional core-cross-linked hybrid micelle system based on mPEG- b-PGu(BA-TPE) and OCT-PEG- b-PGu(DA-TPE)… read more here.
Keywords: core cross; cross linked; neuroendocrine neoplasms; linked micelles ... See more keywords
Core-Cross-Linking of Polymeric Micelles by Di-para-Substituted S-Aroylthiooximes as Linkers for Controlled H2S Release.
Sign Up to like & getrecommendations! Published in 2022 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.2c00137
Abstract: As one of the gasotransmitters, the therapeutic effects of hydrogen sulfide (H2S) were reported widespread in recent years. Considering the short physiological half-life and significant dose-dependent effects of H2S, it is vital to achieve controlled… read more here.
Keywords: cross linking; core cross; cross; polymeric micelles ... See more keywords
Core cross-linked double hydrophilic block copolymer micelles based on multiple hydrogen-bonding interactions
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c7py00210f
Abstract: A facile route for the preparation of core cross-linked polymeric micelles via self-complementary multiple hydrogen bonds was developed. Double hydrophilic block copolymers of poly(ethylene glycol)-b-poly(N-isopropylacrylamide) (PEG-b-PNIPAm), with 2-ureido-4[1H]-pyrimidinone (UPy) functionality throughout PNIPAm block, were synthesized… read more here.
Keywords: block; cross linked; cross; core cross ... See more keywords
Anionic multiblock core cross-linked star copolymers: Via RAFT polymerization
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c7py01062a
Abstract: Poly(2-acrylamido-2-methylpropane sulfonic acid) is a polyelectrolyte currently used in numerous industrial applications. Herein, we report the use of reversible addition fragmentation chain transfer (RAFT) polymerization to prepare a range of well-defined homopolymers and block copolymers… read more here.
Keywords: polymerization; cross linked; multiblock core; cross ... See more keywords
Continuous flow synthesis of core cross-linked star polymers via photo-induced copper mediated polymerization
Sign Up to like & getrecommendations! Published in 2019 at "Polymer Chemistry"
DOI: 10.1039/c9py00134d
Abstract: A convenient method to synthesize core cross-linked star polymers via a continuous flow photopolymerization process is developed. read more here.
Keywords: polymers via; star polymers; continuous flow; cross linked ... See more keywords