Complex Structures Made Simple – Continuous Flow Production of Core Cross‐Linked Polymeric Micelles for Paclitaxel Pro‐Drug‐Delivery
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210704
Abstract: Translating innovative nanomaterials to medical products requires efficient manufacturing techniques that enable large‐scale high‐throughput synthesis with high reproducibility. Drug carriers in medicine embrace a complex subset of tasks calling for multifunctionality. Here, the synthesisof pro‐drug‐loaded… read more here.
Keywords: pro drug; core cross; cross; continuous flow ... See more keywords
Impact of Polyethylene Glycol (PEG) Conformations on the In Vivo Fate and Drug Release Behavior of PEGylated Core-Cross-Linked Polymeric Nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00730
Abstract: In cancer chemotherapy, core-cross-linked particles (CCPs) are a promising drug carrier due to their high structural stability in an in vivo environment, resulting in improved tumor delivery. A biocompatible polymer of polyethylene glycol (PEG) is… read more here.
Keywords: core; cross linked; polyethylene glycol; core cross ... See more keywords
Octreotide-Conjugated Core-Cross-Linked Micelles with pH/Redox Responsivity Loaded with Etoposide for Neuroendocrine Neoplasms Therapy and Bioimaging with Photoquenching Resistance.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b01827
Abstract: The study of multifunctional polymer micelles combined with chemotherapy due to reduced systemic toxicity and enhanced efficacy has attracted intensive attention. Herein, a multifunctional core-cross-linked hybrid micelle system based on mPEG- b-PGu(BA-TPE) and OCT-PEG- b-PGu(DA-TPE)… read more here.
Keywords: core cross; cross linked; neuroendocrine neoplasms; linked micelles ... See more keywords
Core-Cross-Linking of Polymeric Micelles by Di-para-Substituted S-Aroylthiooximes as Linkers for Controlled H2S Release.
Sign Up to like & getrecommendations! Published in 2022 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.2c00137
Abstract: As one of the gasotransmitters, the therapeutic effects of hydrogen sulfide (H2S) were reported widespread in recent years. Considering the short physiological half-life and significant dose-dependent effects of H2S, it is vital to achieve controlled… read more here.
Keywords: cross linking; core cross; cross; polymeric micelles ... See more keywords
Core cross-linked double hydrophilic block copolymer micelles based on multiple hydrogen-bonding interactions
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c7py00210f
Abstract: A facile route for the preparation of core cross-linked polymeric micelles via self-complementary multiple hydrogen bonds was developed. Double hydrophilic block copolymers of poly(ethylene glycol)-b-poly(N-isopropylacrylamide) (PEG-b-PNIPAm), with 2-ureido-4[1H]-pyrimidinone (UPy) functionality throughout PNIPAm block, were synthesized… read more here.
Keywords: block; cross linked; cross; core cross ... See more keywords
Anionic multiblock core cross-linked star copolymers: Via RAFT polymerization
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c7py01062a
Abstract: Poly(2-acrylamido-2-methylpropane sulfonic acid) is a polyelectrolyte currently used in numerous industrial applications. Herein, we report the use of reversible addition fragmentation chain transfer (RAFT) polymerization to prepare a range of well-defined homopolymers and block copolymers… read more here.
Keywords: polymerization; cross linked; multiblock core; cross ... See more keywords
Continuous flow synthesis of core cross-linked star polymers via photo-induced copper mediated polymerization
Sign Up to like & getrecommendations! Published in 2019 at "Polymer Chemistry"
DOI: 10.1039/c9py00134d
Abstract: A convenient method to synthesize core cross-linked star polymers via a continuous flow photopolymerization process is developed. read more here.
Keywords: polymers via; star polymers; continuous flow; cross linked ... See more keywords