Articles with "core engagement" as a keyword



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Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation

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Published in 2017 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e16-12-0818

Abstract: For a prototypical GPCR, the human vasopressin receptor type 2 (V2R), βarr1 can form a stable complex associated via only the phosphorylated carboxyl terminus of the receptor. Such a partially engaged complex is functionally competent… read more here.

Keywords: arrestin dispensable; engagement arrestin; activation; receptor ... See more keywords