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Published in 2017 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2016.166
Abstract: Histone variants endow chromatin with unique properties and show a specific genomic distribution that is regulated by specific deposition and removal machineries. These variants — in particular, H2A.Z, macroH2A and H3.3 — have important roles…
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Keywords:
variants core;
core histones;
roles cell;
cancer ... See more keywords
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Published in 2021 at "Current Genomics"
DOI: 10.2174/1389202922666210601094643
Abstract: Histones are basic elements of the chromatin, and are critical to controlling chromatin structure and transcription. The proteasome activator PA200 promotes the acetylation-dependent proteasomal degradation of the core histones during spermatogenesis, DNA repair, transcription and…
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Keywords:
degradation;
transcription;
blm10;
core histones ... See more keywords
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Published in 2022 at "Life Science Alliance"
DOI: 10.26508/lsa.202201614
Abstract: This work reported that there is a global loss of core histones and progressively reduced telomere silencing during yeast chronological aging and uncovered the core histones-autophagy-Sir2 pathway that contributes to the aging-coupled loss of telomere…
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Keywords:
sir2 axis;
core histones;
histones autophagy;
autophagy sir2 ... See more keywords