A dynamic hydrophobic core orchestrates allostery in protein kinases
Sign Up to like & getrecommendations! Published in 2017 at "Science Advances"
DOI: 10.1126/sciadv.1600663
Abstract: The synchronized motions of inner core residues allosterically modulate the activity of the protein kinase A catalytic subunit. Eukaryotic protein kinases (EPKs) constitute a class of allosteric switches that mediate a myriad of signaling events.… read more here.
Keywords: protein; hydrophobic core; core orchestrates; protein kinases ... See more keywords