Correlating histone acetylation with nucleosome core particle dynamics and function.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2301063120
Abstract: Epigenetic modifications of chromatin play a critical role in regulating the fidelity of the genetic code and in controlling the translation of genetic information into the protein components of the cell. One key posttranslational modification… read more here.
Keywords: acetylation; core particle; histone; nucleosome core ... See more keywords
Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab644
Abstract: Abstract Giardia lamblia is a pathogenic unicellular eukaryotic parasite that causes giardiasis. Its genome encodes the canonical histones H2A, H2B, H3, and H4, which share low amino acid sequence identity with their human orthologues. We… read more here.
Keywords: core particle; lamblia histones; lamblia; giardia lamblia ... See more keywords
Chaperone-mediated assembly of the proteasome core particle - recent developments and structural insights.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259622
Abstract: Much of cellular activity is mediated by large multisubunit complexes. However, many of these complexes are too complicated to assemble spontaneously. Instead, their biogenesis is facilitated by dedicated chaperone proteins, which are themselves excluded from… read more here.
Keywords: chaperone mediated; core particle; structural insights; particle ... See more keywords